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TitleThe function of the BRCA2 protein and centriole mobility during cytokinesis studied with live-cell
LanguageEnglish
File Size3.8 MB
Total Pages134
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Ásta Björk Jónsdóttir







The function of the BRCA2 protein and centriole
mobility during cytokinesis studied with live-cell

microscopy



















PhD THESIS

UNIVERSITY OF ICELAND

FACULTY OF MEDICINE

November 2010

Page 68

46

thorough studies on the chromosomal aberrations and the presence of anaphase-

bridges in cells heterozygous for a mutation in the BRCA2 gene might explain

whether they induce a delay in cytokinesis.

Collectively, the data in this study indicate that defects in cytokinesis can contribute

to the increased cancer susceptibility in carriers of a BRCA2 mutation.

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Jonsdottir AB et al.

Figure 1

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Jonsdottir AB et al.

Figure 2

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