Download Atlas of Forensic Histopathology - P. Cummings, et. al., (Cambridge, 2011) WW PDF

TitleAtlas of Forensic Histopathology - P. Cummings, et. al., (Cambridge, 2011) WW
TagsMedical
LanguageEnglish
File Size39.8 MB
Total Pages200
Table of Contents
                            Contents
Foreword
Preface
Acknowledgement
1 Post-injury intervals
	Introduction
	Contusion dating
		Skin
		Brain
			Subarachnoid hemorrhage dating
				Cerebral contusion dating
	Hypoxic/ischemic injury and increased intracranial pressure
	Brain incidentals (non-injurious)
	Sexual violence
2 Decomposition
	Introduction
	Heart
	Lung
	Liver
	Kidney
	Pancreas
	Esophagus
	Skin
	Deep vein thrombosis
3 Thrombotic and embolic lesions
	Introduction
	Thromboembolism
	Tissue/foreign body emboli
		Fat embolism
		Amniotic fluid embolism
4 Aspiration and drowning
	Introduction
	Fluid
	Food
5 Poisoning
	Introduction
	Ethylene glycol poisoning (oxalate in kidney tubules)
	Acid ingestion
	Chronic injection sequelae
	Ethanol
	Cocaine
	Salicylates
6 Injuries
	Introduction
	Gunshot wounds
	Thermal injuries
	Cold
	Electrical
7 Sudden death
	Introduction
	Cardiovascular system
		Hypertension
		Myocardial infarction
			Subacute infarction
		Stigmata of heart failure
		Coronary artery atherosclerosis
	Cerebral vascular sequelae of hypertensive and atherosclerotic cardiovascular disease
		Stigmata of cerebral vascular catastrophes
	Conduction system abnormalities
	Hypertrophic cardiomyopathy
	Infiltrative diseases
	Inflammatory disease
	Epilepsy
	Diabetes Mellitus
	Allergy
	Pulmonary
	Asthma
	Sickle cell disease
	Miscellaneous infectious/inflammatory disease
	AcquireD Immune Deficiency Syndrome
8 Pediatrics: special topics
	Introduction
	Fetal demise (how long in utero after death)
	Inflicted injury
		A few words about radiology and injury
		A few words about axonal injury
	Fracture Dating
		A few words about retinal hemorrhages
		Not to be confused with skin contusions
Index
                        
Document Text Contents
Page 2

AT L A S O F F O R E N SIC
H I S T O PAT HO L O G Y

Page 100

chapter 6: InjurIes

85

Figure 6.9a. Heart. There is
coagulative necrosis of the
myocardium with areas of
increased eosinophilia that
have a similar appearance to
contraction band necrosis
(arrows). However, unlike
contraction bands, the
increased eosinophilia is
affecting the entire cardiac
myocyte. There is some
streaming of nuclei.

Figure 6.9B. A higher-power
view.

Page 101

chapter 6: InjurIes

86

Figure 6.10. Dura. The
tinctoral properties have
changed and become more
eosinophillic. There is
streaming of the nuclei of the
cells within the dura.

Figure 6.11. Cerebral cortex.
There is necrosis of the
leptomeninges, which are
shrunken and show increased
eosinophilia (arrow). The
leptomeningeal arteries
appear hyalinized, a finding
that is created by heat artifact.
There is artificial clearing
around the cortical neurons
that should not be confused
with edema.

Page 199

Index

184

fat embolism, 42–43
pulmonary embolism, 38

emphysema aquosm, 48
endocarditis, 57–60
eosinophilia, 15, 18

myocardial infarction, 100, 103
thermal injury, 84, 85

eosinophilic myocarditis, 129–30
ependymal rests, 23
epilepsy, 131–35
erythrocyte “laking”, 2
esophagus, decompositional changes, 34
ethanol abuse, 70–76

central pontine myelinolysis, 73
cerebellar atrophy, 70–71
chronic pancreatitis, 72–73
necrotic and cirrhotic liver, 75–76
steatohepatitis, 71, 74
Wernicke’s encephalopathy, 74

ethylene glycol poisoning, 54–57

fat embolism, 36, 42–43
fatty metamorphosis, 107
fetal demise, 154–59

estimating time of death, 164
fibrin thrombi, 39
fibroblasts, 11
fibrosis, 92

arrhythmogenic right ventricular
dysplasia (ARVd), 125

cocaine abuse and, 76
decomposition and, 29, 32
ethanol abuse and, 71, 72, 73, 75
hypertrophic cardiomyopathy, 126
myocardial infarction, 107, 108, 109
myocarditis, 128
pericarditis, 128
pulmonary, 137

bronchopneumonia, 145
fire-related injuries, 83–87
food aspiration, 49–52
foreign body giant cells, 66, 68, 69

giant capillaries, 13
Glial Fibrillary Acidic Protein (GFAP), 132
glial-neuronal heterotopia of the

leptomeninges, 164
gliosis, 18, 22, 118
gliotic cyst, 16
glomerulosclerosis, 32
granulation tissue, 105, 106
gunshot wounds, 81–82

heart. See also cardiovascular disease
after prolonged cardiopulmonary

resuscitation efforts, 110
Cryptococcus infection, 151

decompositional changes, 29
fetal demise, 157
thermal injury, 85

heart failure, 118
chronic, 111

hemorrhage
acute bacterial endocarditis, 60
amyloid angiopathy, 121
axonal injury, 167
bladder infection, 147
brain abscess, 63
carotid artery dissection, 96
cerebral contusion, 14, 15, 16
chronic injection sequelae, 68, 69
eosinophilic myocarditis, 129
heart failure, 112
hypothermia and, 88
myocardial infarction, 99, 103, 104
necrotic liver, 75, 76
pontine avulsion, 17
pulmonary, 140
retinal, 172–74
retroperitoneal, 165–66
skin contusion, 2
skull fracture, 170
subarachnoid, 5
subdural, 6–13

acute, 8, 9, 12
uncal herniation, 19

hemosiderin
cerebral contusion, 16
cerebral vascular disease, 118, 119
heart failure, 111
myocardial infarction, 106, 109
pulmonary infarction, 40
subdural hematoma, 9, 10, 12

hippocampus, in epilepsy, 131, 132
hypertension, 93–98, 107

carotid artery dissection, 96–97
cerebral vascular changes, 118
kidney changes, 33
pulmonary, 139
right ventricular hypertrophy, 95

hypertrophic cardiomyopathy, 126
hypothermia, 88
hypoxic injury, 18–21

ibuprofen toxicity, 77
infectious diseases. See also specific

diseases, 144–51
injection sequelae. See chronic injection

sequelae
injuries, 80

cold-induced, 88
electrical, 89–91
gunshot wounds, 81–82
pediatric, 164–75

axonal injury, 166–69

radiology, 164
retinal hemorrhages, 172–74
retroperitoneal hemorrhage, 165–66
skull, 170–71

thermal injuries, 83–87
intracranial pressure (ICP), increased

duret hemorrhages, 20
uncal herniation, 19

intravenous drug abuse. See chronic
injection sequelae

ischemic injury, 18–21

Kaposi sarcoma, 150–51
kidney

autolysis, 31
calcium oxalate crystals, 54–55
decompositional changes, 31–33
fetal demise, 155–56
hypertensive changes, 97
infant, 161–62
ischemia from circulatory

collapse, 33
thermal injury, 84

Kimmelstiel-Wilson lesions, 33, 136

lacunar infarct, remote, 119
laminar necrosis, 20, 21
leptomeninges

glial-neuronal heterotopia of, 164
thermal injury, 86

lines of Zahn, 37, 38
liver

acetaminophen toxicity, 78
alcoholic steatohepatitis, 71, 74
chronic injection sequelae, 64–65
cirrhosis, 31, 75–76
decompositional changes, 30–31
fetal demise, 158
heart failure and, 112–13
thermal injury, 84
triaditis, 64

lung, 41
alveolar damage, 137–38
decompositional changes, 30
fetal demise, 158–59
infant, 162

atelectatic, 163
viral, 163

pulmonary infarct, 40
sickle cell disease, 142
smoker’s, 139

lymphocytic myocarditis, 127–28
lymphocytic pericarditis, 128–29

meningeal artery, 8, 9
meningitis, bacterial, 146
mineralization, 25, 118, 120
Mongolian spot, 175

embolic lesions (continued)

Page 200

Index

185

myelinating glia, 22
myocardial infarction, 98–110

acute, 104
cocaine related, 76
remote, 111
subacute, 104–06
temporal alterations, 98

myocardial scar, 107
myocarditis

acute, 64, 127–28
eosinophilic, 129–30
lymphocytic, 127–28

necrosis
acetaminophen toxicity, 78
acute bacterial endocarditis, 59
brain abscess, 63
electrocution and, 89
heart failure, 112, 113
kidney ischemia, 33
laminar, 20, 21
liver, 75–76
myocardial infarction, 100, 101, 103
pulmonary, 40, 137
thermal injury, 83, 84, 85, 86

neovascularization, 8
nutmeg liver, 113

opiate intoxication, 18
optic nerve hemorrhage, 174
organizing thrombus, 38

pancreas
decompositional changes, 33
hypothermia, 88

pancreatitis, chronic, 72–73
pediatrics, 153, 161–64

fetal demise, 154–59
inflicted injuries, 164–75

axonal injury, 166–69
radiology, 164
retinal hemorrhages, 172–74
retroperitoneal hemorrhage,

165–66
skull, 170–71

rib fracture healing, 171
pericarditis, lymphocytic, 128–29

pineal cyst, 133–34
pinocytoma, 132–33
placenta, 159
Pneumocystis carinii pneumonia (PCP),

149–50
pneumonia. See bronchopneumonia;

Pneumo cystis carinii pneumonia
(PCP)

poisoning, 53
chronic injection sequelae, 57–69
cocaine, 76
ethanol, 70–76
ethylene glycol, 54–57
salicylates, 77–78

pontine avulsion, 17
popliteal vein thrombosis, 37
post injury intervals. See dating of

injuries
pulmonary artery atheroma, 94–95
pulmonary disease. See also specific

diseases, 137–40
pulmonary embolism, 38
pulmonary hypertension, 139
pulmonary infarct, 40
Purkinje cells, 24, 70, 87
putrefaction, 28
pyknosis, 15, 18

retinal hemorrhages, 172–74
retroperitoneal hemorrhage,

165–66
rib fracture healing in infants, 171
right ventricular hypertrophy, 95
Rosenthal fibers, 133

SA node, 124
sagittal sinus, 6, 7
salicylate poisoning, 77–78
sexual intercourse, evidence of, 27
sickle cell disease, 141–43
sinoatrial artery, 124
skin

cutaneous injection site, 68–69
dating of injuries, 2–3
decompositional changes, 34
electrocution and, 89–91
gunshot wound, 82

skull
fracture, 170
suture, 170–71

smoker’s lung, 139
soot inhalation, 83
spermatozoa, 27
spinal cord

gunshot wound, 81
tooth paste artifact, 26

spleen
infarct, 61
sickle cell disease, 142

steatohepatitis, alcoholic, 71, 74
stomach, hypothermia and, 88
subarachnoid hemorrhage

dating, 5
subdural hemorrhage

acute, 8
dating, 6–13

substance abuse. See poisoning
sudden death, 92–93

thermal injuries, 83–87
thromboembolism, 37–42

pulmonary embolism, 38
pulmonary infarct, 40

thrombotic lesions.
See also thromboembolism, 36

coronary artery thrombosis, 115, 116
dating, 116

fibrin thrombi, 39
organizing thrombus, 38
popliteal vein thrombosis, 37
postmortem blood clot, 42

antemortem vs. postmortem
clots, 36

tooth paste artifact of the spinal cord,
26

trachea, thermal injury, 83
trigona fibrosa, 123
tubulorrhexis, 33

uncal herniation, 19
urinary bladder infection, 147–48

Wernicke’s encephalopathy, 74
Wisnewski’s ulcers, 88

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